see the simplified story here

 

We have a general interest in development and application of innovative technologies for characterising different molecular layers, including (epi)genome and transcriptome, at the single-cell resolution. We further decipher the connectivity and interplay between those molecular layers within a single cell and their impact on cellular identity and function. We constantly explore new avenues towards translating our research into the clinic.

 

The lab is specifically focused on studying (epi)genome  (in)stability in early human development with application to the clinic, e.g. preimplantation genetic testing (PGT) and non-invasive prenatal testing (NIPT). Our research lies at the intersection of classical genetics, molecular and developmental genetics, clinical genetics, bioinformatics and artificial intelligence. 

Fertilization

Chromosome instability (CIN)

 

Team

Masoud Zamani Esteki
Principal investigator
 
See Masoud's vision here
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Your name
Postdoc scientist
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Medical machine learning​
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Rebekka Koeck
PhD candidate
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Cellular omics
Lisa Sackmann 
Internship student​
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Embryonic mosaicism
Jeroen Meekels 
Senior research technician
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Single-cell genomics
Nina Rodenburg
Internship student​
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Non-invasive genetic testing
Rick Essers
PhD candidate
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Genomic organization
Shanna Overeem 
Internship student​
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Clinical Epigenomics​
Dominique Pellaers
PhD candidate
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Liquid biopsy

Alumni

  • Gaby Schobers (postgraduate student)

  • Britt Thomassen (undergraduate student)

  • Jesko Wagner (undergraduate student)

Contact

Email: masoud.zamaniesteki@mumc.nl
Tel:  +31 43 38 75306
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Address:
Cellular Genomic Medicine
Department of Clinical Genetics
Maastricht UMC+

P. Debyelaan 25

6229 HX Maastricht

The Netherlands

 

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