We have a general interest in development and application of innovative technologies for characterising different molecular layers, including (epi)genome and transcriptome, at the single-cell resolution. We further decipher the connectivity and interplay between those molecular layers within a single cell and their impact on cellular identity and function. We constantly explore new avenues towards translating our research into the clinic.
The lab is specifically focused on studying (epi)genome (in)stability in early human development with application to the clinic, e.g. preimplantation genetic testing (PGT) and non-invasive prenatal testing (NIPT). Our research lies at the intersection of classical genetics, molecular and developmental genetics, clinical genetics, bioinformatics and artificial intelligence.
Chromosome instability (CIN)
Senior research technician
Ethics of innovations in Reproductive Medicine
Emma Zwilling (postgraduate student)
Sanne Romans (undergraduate student)
Nina Rodenburg (undergraduate student)
Lisa Sackman (undergraduate student)
Shanna Overeem (undergraduate student)
Gaby Schobers (postgraduate student)
Britt Thomassen (undergraduate student)
Jesko Wagner (undergraduate student)